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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells

Fig. 1

Loss of normal-p53 induces AMAP1 expression in MDA-MB-231 and HMLE cells. a Expression levels of AMAP1 and p53 were assessed by immunoblotting (left). The ratio of AMAP1/Actin was analyzed by densitometry and the results (right) are shown as the mean ± SEM (n = 2). n.s. means no significance. *P < 0.05. b Relative units of AMAP1 mRNA were measured by quantitative-PCR. The mRNA level of MDA-MB-231 cells (parental) was used as a reference value for the other cell lines. The results are shown as the mean ± SEM (n = 3, HMLE series, n = 2, MDA-MB-231). *P < 0.05

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