Fig. 8
From: Regulation of MRTF-A by JMY via a nucleation-independent mechanism
Depletion of JMY reduces MRTF activity a: NIH 3 T3 mouse fibroblasts were transfected with control siRNA and JMY-specific siRNA and analyzed for MRTF-SRF activation upon stimulation with TGF-β1 or FCS. b: Knock-down efficiency of JMY-specific siRNA was validated by immunoblotting with JMY-antibody and tubulin as a control. Data are normalized to siRNA control. Error bars, s.e.m., n = 3 (* p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001 according to an unpaired two sample student’s t-test)