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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells

Fig. 5

CDH3 expression predicts sensitivity to dasatinib treatment. a Correlation between CDH3 gene expression and IC50 values for dasatinib treatment in Luminal and Basal A BCC lines. The data was retrieved from a previously published gene expression profile using 23 breast cancer cell lines to identify genomic signatures highly correlated with in vitro sensitivity to dasatinib (GEO accession number: GSE6569). b CDH3 gene expression values in dasatinib sensitive and resistant prostate cancer cells. The data was retrived using a dataset of baseline gene expression profiling of 16 prostatic cancer cell lines used to identify expression signatures highly correlated with in vitro sensitivity to dasatinib (GEO accession number: GSE9633 [25])

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