Copper signalling: causes and consequences

Table 2 Average concentration of copper in different brain areas

	Bonilla 1984 [77]	Harrison et al. [78]	Ramos et al., [81]	Pal et al. [80]
	FAAS	AAS	ICP-MS	AAS
	μg/g dry tissue	μg/g dry tissue	μg/g dry tissue	μg/g wet tissue
Frontal pole	18.95
Precentral gyrus	8.68
Occipital pole	21.61
Calcarine cortex	23.07
Postcentral gyrus	18.83
Supramarginal gyrus	16.45
Uncus	16.30
Cingulate gyrus	15.14		57
Mammilay bodies	19.65
Superior colliculus	15.38
Inferior colliculus	17.92
Olfactory tract	17.66
Olfactory bulb	27.92
Optic nerve	17.79
Optic chiasm	7.06
Caudate nucleus (head)	13.49	42	61
Caudate nucleus (body)	18.46
Caudate nucleus (tail)	23.12
Putamen	14.62	44	62
Globus pallidus	12.47	35	45
Thalamus	8.75	21
Frontal lobe, white matter	5.43	22	36
Frontal lobe, gray matter	5.43	38	36
Occipital lobe, white matter	8.88		55
Parietal lobe, white matter	7.27		60
Temporal lobe, white matter	11.12
Red nucleus	10.41
Substantia nigra	17.42
Inferior olivary nucleus	12.00
Superior olivary nucleus	17.46
Pineal gland	17.81
Cerebellum (vermal cortex, superior half)	10.92
Cerebellum (vermal cortex, inferior half)	15.52
Hippocampus		29	70
Corpus callosum		14
Cerebellum, gray matter		47	36	2.69
Cerebellum, white matter		22	36
Frontal cortex			62
Superior temporal gyrus			61
Middle temporal gyrus			68
Midbrain			38
Pons			33
Medulla			35
Cortex				2.20
Striatum				2.18

ISSN: 1478-811X