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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells

Fig. 2

MCP-1 mRNA expression and release from human vascular endothelial cells. a qPCR analyses depicting the relative expression of MCP-1 mRNA after exposure to IL-6 (100 ng/ml) alone or in combination with sIL-6R (200 ng/ml). b ELISA data showing the MCP-1 release into medium (48 h) induced by increasing concentrations of IL-6 alone or in combination with sIL-6R. Data is presented as mean ± SEM of 3 experiments each run-in duplicate. *p < 0.05, **p < 0.01 compared to its respective control

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