Table 4 proteins/RNA interact with FOXM1
Protein/RNA | Binding site | Effect | Cell cycle | FOXM1 isoform |
|---|---|---|---|---|
B55α [61] | a | CyclinA CDK2 activity↓ | G1 | FOXM1c |
RB [85] | 359/425 | Transcriptional activity↓ | G1 | FOXM1c |
p19ARF [86] | 688/748 | Transcriptional activity↓ |  | FOXM1b |
NPM [87] | 195/688 | Nuclear translocation↑ |  | FOXM1b |
CDC25A [89] | C-terminal | CDK1 activity↑ |  | FOXM1 |
PHGDH [133] | N-terminal | Stabilization↑ |  | FOXM1 |
MELK [88] | N-terminal | Plk1 activity↑ | G2 → M/M | FOXM1 |
Pin1 [134] | S331,704 | Transcriptional activity↑ |  | FOXM1 |
MTDH [90] | N-terminal | Stabilization↑ transcriptional activity↑ |  | FOXM1b |
PVT1(lncRNA) [91] | a | Stabilization↑ |  | FOXM1 |
HSP70 [135] | a | Transcriptional activity↓ |  | FOXM1 |