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Table 4 proteins/RNA interact with FOXM1

From: Regulation of the master regulator FOXM1 in cancer

Protein/RNA Binding site Effect Cell cycle FOXM1 isoform
B55α [61] a CyclinA CDK2 activity↓ G1 FOXM1c
RB [85] 359/425 Transcriptional activity↓ G1 FOXM1c
p19ARF [86] 688/748 Transcriptional activity↓   FOXM1b
NPM [87] 195/688 Nuclear translocation↑   FOXM1b
CDC25A [89] C-terminal CDK1 activity↑   FOXM1
PHGDH [133] N-terminal Stabilization↑   FOXM1
MELK [88] N-terminal Plk1 activity↑ G2 → M/M FOXM1
Pin1 [134] S331,704 Transcriptional activity↑   FOXM1
MTDH [90] N-terminal Stabilization↑ transcriptional activity↑   FOXM1b
PVT1(lncRNA) [91] a Stabilization↑   FOXM1
HSP70 [135] a Transcriptional activity↓   FOXM1
  1. CD central domain
  2. a not clear
  3. ↓ Decrease
  4. ↑ Increase
  5. → Transition