TY - JOUR AU - Yu, Changsun AU - Kim, Bok-seok AU - Park, Minyoung AU - Do, Yun-Ju AU - Kong, Young-Yun AU - Kim, Eunhee PY - 2018 DA - 2018/09/10 TI - FAF1 mediates necrosis through JNK1-mediated mitochondrial dysfunction leading to retinal degeneration in the ganglion cell layer upon ischemic insult JO - Cell Communication and Signaling SP - 56 VL - 16 IS - 1 AB - Aberrant cell death induced by ischemic stress is implicated in the pathogenesis of ischemic diseases. Fas-associated factor 1 (FAF1) has been identified as a death-promoting protein. This study demonstrates that FAF1 functions in death signaling triggered by ischemic insult. SN - 1478-811X UR - https://doi.org/10.1186/s12964-018-0265-7 DO - 10.1186/s12964-018-0265-7 ID - Yu2018 ER -