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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Chemotherapy induced PRL3 expression promotes cancer growth via plasma membrane remodeling and specific alterations of caveolae-associated signaling

Fig. 4

PRL3 expression affects integrin ß1 phosphorylation (a) Integrin ß1 shows dephosphorylation at Thr788/789 upon the induction of PRL3 expression with doxycycline. (b) Raft fractions corresponding to the caveolae region of the membrane from doxycycline-induced B16F0-PRL3 cells were analyzed for the presence of integrin ß1. Only the 150 KDa form of integrin ß1 is present in the caveolae membrane fraction and it cofractionates with PRL3

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Cell Communication and Signaling

ISSN: 1478-811X