Fig. 1

WTAP is overexpressed in DLBCL. a Representative H&E-stained, WTAP (brown) -stained sections of DLBCL tissues; Different grades in the intensity of WTAP staining are presented. b H&E-stained and WTAP-stained sections of lymphoid tissues. c States of WTAP protein expression in patients (n = 30) is significantly higher than in normal lymphoid tissues (n = 30) (***P < 0.001, Student’s t-test). These sections were evaluated by two pathologists (double blinded). A staining index (values 0–12) were obtained for the intensity of WTAP-positive staining (negative, 0; weak 1; moderate, 2; or strong, 3 scores) and the proportion of immunopositive cells (< 25%, 1; 25–50%, 2; 50–75%, 3; > 75%, 4 scores) was calculated