Table 1 Selection of Ras superfamily members. Selection of family members based on domain predictions using the SMART or Pfam databases, or based on Rojas et al., 2012

Ras family

DIRAS1

YES

YES

YES

DIRAS2

YES

YES

YES

DIRAS3

NO

YES

YES

ERAS

YES

YES

YES

GEM

NO

YES

YES

HRAS

YES

YES

YES

KRAS

YES

YES

YES

MRAS

YES

YES

YES

NKIRAS1

NO

YES

YES

NKIRAS2

NO

YES

YES

NRAS

YES

YES

YES

RALA

YES

YES

YES

RALB

YES

YES

YES

RAP1A

YES

YES

YES

RAP1B

YES

YES

YES

RAP2A

YES

YES

YES

RAP2B

YES

YES

YES

RAP2C

YES

YES

YES

RASD1

YES

YES

YES

RASD2

YES

YES

YES

RASL10A

NO

YES

YES

RASL10B

NO

YES

YES

RASL11A

NO

YES

YES

RASL11B

NO

YES

YES

RASL12

NO

YES

YES

REM1

NO

YES

YES

REM2

NO

YES

YES

RERG

YES

YES

YES

RERGL

NO

YES

YES

RHEB

YES

NO

YES

RHEBL1

YES

NO

YES

RIT1

YES

NO

YES

RIT2

YES

NO

YES

RRAD

NO

YES

YES

RRAS

YES

YES

YES

RRAS2

YES

YES

YES