Fig. 4
From: Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors
Administration of IL-15 enhances collagen deposition in injured muscles. a A schematic showing the experiment in vivo: IL-15 (or combination with Jak inhibitor) was administered from 1dpi to 3 dpi and samples were sectioned on 5 dpi. b Immunofluorescence for collagen I after administration of IL-15 in injured muscle 5 dpi. Scale bar, 20 μm. c Quantification of collagen deposition area (shown in percentage). d qPCR analysis of fibrosis-associated biomarkers, Fn1 and collagen I, in injured muscle with glycerol injection 5 dpi. Abbreviations: Gly, glycerol; Colla 1, Collagen I