Fig. 5
From: Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas
a Interstitial fluid pressure (PIF) in KAT-4 carcinomas treated with 3G9 at 3 (n = 8), 10 (n = 9), or 30 (n = 9) mg/kg, or with Fc:TβRII (10 mg/kg) (n = 9). PBS was used as negative control (n = 7). b Interstitial fluid pressure (PIF) in Capan-2 tumors treated three times with 3G9 (n = 5) or with 3G9 long term (n = 6) at10 mg/kg. PBS was used as control (n = 11). c CD31-stained structures with an area > 29 μm2 to avoid potential non-vascular CD31 positive structures in PBS- (n = 7) and 3G9-treated (n = 3) KAT-4 carcinomas. d CD31-stained structures measured as in C, but in PBS- (n = 4) and 3G9-treated (n = 5) Capan-2 carcinomas. Error bars are standard deviations