Fig. 5
From: Peptides derived from the integrin β cytoplasmic tails inhibit angiogenesis
Identify the antiangiogenic core region in mβ3CTP. a The amino-acid sequences of different mβ3CTP variants with sequential residue deletions from either side of β3CTP were shown. b, c HUVECs were seeded on polymerized Matrigel in 24-well plates and treated with the indicated mβ3CTP variants (20 μM at a final concentration) or PBS alone as a control. The formed capillary-like structures were counted under an inverted microscope (5× objective). Results were expressed as means ±SD from three experiments; statistical significance was analyzed using Student’s t test (**, p < 0.01)