Skip to main content
Fig. 2 | Cell Communication and Signaling

Fig. 2

From: In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself

Fig. 2

Influence of PTEN-Δ expression on tumor progression of RCC patients. PTEN-Δ and PTEN expression was quantified by Real-Time PCR in tumor tissue specimens from patients with primary RCC, shock frozen after nephrectomy. Patients were grouped in two categories: patients with a high PTEN-Δ or PTEN expression value (PTEN-Δ / PTEN > median) and in a group with low PTEN-Δ or PTEN expression value (PTEN-Δ / PTEN ≤ median). a The Kaplan-Meier curves show the lymph node metastasis rate of patients with high PTEN-Δ or PTEN expression value compared to patients with a low PTEN-Δ or PTEN expression in RCC tissue. Significance was calculated by a Log Rank test, p < 0.05. b The Kaplan-Meier curves show the overall survival of patients with high/low PTEN-Δ or PTEN expression value in RCC tissue. Significance was calculated by a Log Rank test, p < 0.05. c Comparison of time to death of patients with high PTEN-Δ and simultaneously high PTEN expression value (> median) and patients with low PTEN-Δ and simultaneously low PTEN expression (< median). Significance was calculated by a Mann-Whitney-U test, p < 0.05

Back to article page