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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself

Fig. 1

Schematic illustration of PTEN-Δ and PTEN. The nine exons of the PTEN gene are represented as boxes. PTEN-Δ lacks the coding potential of exon 9 due to inclusion of intron 8. The PTEN protein is composed of five domains: PBD-, Phosphatase, C2-, C-tail- and PDZ-binding Domain, PTEN-Δ consequently lacks parts of the C2 domain, the C-tail and the PDZ-binding domain

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Cell Communication and Signaling

ISSN: 1478-811X