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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1

Fig. 8

MiR-644a overexpression inhibits xenograft HCC tumour growth. (a) Representative images of xenograft tumours from nude mice subcutaneously injected with SMMC-7721 cells stably transfected with miR-644a mimic or control miRNA. (b) Xenograft tumour weights from nude mice subcutaneously injected with SMMC-7721 cells stably transfected with miR-644a mimic or control miRNA. (c) Representative images (400×) of IHC staining of HSF1 in xenograft tumours derived from SMMC-7721 cells stably transfected with miR-644a mimic or control miRNA. (d) Representative western blot shows HSF1 expression in xenograft tumours derived from SMMC-7721 cells stably transfected with miR-644a mimic or control miRNA. Note: * denotes P < 0.05 and ** denotes P < 0.01 compared to controls

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Cell Communication and Signaling

ISSN: 1478-811X