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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1

Fig. 7

MiR-644a/HSF1 axis regulates HCC cell apoptosis via the BH3-only protein signalling pathway. (a) Protein chip clustering analysis shows differential protein expression in control and HSF1 siRNA transfected SMMC-7721 cells. (b) Protein chip enrichment analysis shows signalling pathways differentially regulated by silencing HSF1 in SMMC-7721 cells. (c–d) Representative western blots show expression of apoptosis-related proteins in SMMC-7721 cells transfected with miR-644a mimic or control miRNA. All experiments were repeated three times

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Cell Communication and Signaling

ISSN: 1478-811X