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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1

Fig. 5

HSF1 silencing decreases proliferation and increases apoptosis of HCC cells. (a) CCK8 assay shows proliferation of HepG2 and SMMC-7721 cells transfected with control or HSF1-siRNA. (b) Colony formation assay shows the total number of colonies formed by HepG2 and SMMC-7721 cells transfected with control or HSF1-siRNA. (c) Flow cytometry analysis shows apoptosis of HepG2 and SMMC-7721 cells transfected with control or HSF1-siRNA. Note: * denotes P < 0.05 and ** denotes P < 0.01 compared to controls

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