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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior

Fig. 4

a One hundred thousand cells of NCI-H295R cells were allowed to migrate through a Boyden chamber. Decreased migration activity was noted in NCI-H295R cells undergoing SLC12A7 knock down with siRNA B duplex (*, p < 0.05, one-way ANOVA). Horizontal bar, mean; Error bars, standard error of mean. Migration assays were performed in two independent experiments using 3 wells per each experimental condition analyzed. b One hundred thousand cells of NCI-H295R cells were allowed to invade through a Matrigel layer in a modified Boyden chamber. Decreased invasion activity was noted in NCI-H295R cells undergoing SLC12A7 knock down with siRNA B duplex (*, p < 0.05, one-way ANOVA). Horizontal bar, mean; Error bars, standard error of mean. Invasion assays were performed in two independent experiments using 3 wells per each experimental condition analyzed. c Representative photomicrographs of NCI-H295R invasion undergoing siRNA knockdown are shown right

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Cell Communication and Signaling

ISSN: 1478-811X