From: The design of high affinity human PD-1 mutants by using molecular dynamics simulations (MD)
NO. | PDBID | Species | Length | Resolution (Å) | R-value | Notations | Journal & Released date |
---|---|---|---|---|---|---|---|
1 | 1NPU | mouse | S34-L149(116) | 2.0 | 0.198 | C83S | Immunity, 2004 |
2 | 3BIK | mouse | G30-I148(119) | 2.65 | 0.211 | C83S | PNAS, 2008 |
3 | 3BP5 | mouse | S34-R147(114) | 1.8 | 0.190 | C83S | PNAS, 2008 |
4 | 3BP6 | mouse | S34-T145(112) | 1.6 | 0.184 | C83S,A132L | PNAS, 2008 |
5 | 3RNK | mouse | S34-T145(112) | 1.74 | 0.195 | C83S,A132L | -, 2011 |
6 | 3SBW | mouse | S34-T145(112) | 2.28 | 0.218 | C83S,A132L | -, 2011 |
7 | 3RNQ | mouse | S34-T145(112) | 1.74 | 0.183 | C83S, L128R | -, 2011 |
8 | 3RRQ | human | N33-A149(117) | 2.1 | 0.214 | A132L, E61 missing D85-D92 missing | -, 2011 |
9 | 2M2D | human | M33-E150(118) | NMR | – | C93S, N33 M | JBC, 2013 |
10 | 4ZQK | human | N33-E146(114) | 2.45 | 0.207 | C93S D85-D92 missing | Structure, 2015 |
11 | 5B8C | human | S31-E146(116) | 2.15 | 0.184 | C93S T59-E61 missing | Sci Rep, 2016 |
12 | 5GGR | human | S27-E146(120) | 3.3 | 0.221 | C93S S73-N74missing | Nat Commun, 2016 |
13 | 5GGS | human | P31-E146(116) | 2.0 | 0.179 | C93S | Nat Commun, 2016 |
14 | Human | D29-R147(119) | 2.89 | 0.207 | 11 mutations # | Structure, 2016 | |
14 | 5JXE | human | N33-E146(114) | 2.9 | 0.261 | C93S N58-E61 missing A129-K131 missing | Cell Res, 2017 |
15 | 5WT9 | human | L25-L142 (118) | 2.4 | 0.187 | D85-C93 missing | Nat Commun, 2017 |