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Table 2 Substrates of human CK1α in various biological events

From: Casein kinase 1α: biological mechanisms and theranostic potential

Gene

Protein

Phosphorylation site

Function

Reference

IFNAR1

IFNAR1

S535

Leishmania major/VSV/ IAV

[137, 138, 140]

IFNGR1

IFNGR1

N/A

IAV

[140]

NS5A

NS5A

S232

HCV

[145, 146]

NS5

NS5

S56

YFV

[147]

NSP5

NSP5

S67

Rotavirus

[143, 144]

HNRNPC

hnRNP C1/C2

S240/253, S247/260, S286/S299

mRNA metabolism

[183]

TUT1

Star-PAP, RBM21

S6

[184]

AGO2

AGO2

S824, S828, T830, S831, S834

MiRNA-mediated silencing of target mRNA

[185]

KDM1A

LSD1

S687

Glioblastoma

[173]

PHLPP1

PHLPP1

S1359, T1363, S1379, S1381

Colorectal cancer

[166]

RAPGEF2

RAPGEF2

S1244, S1248

Cancer metastasis

[174]

RXRA

RXRα

N/A

Cancer apoptosis

[175]

Bid

Bid

N/A

[176]