Skip to main content
Fig. 2 | Cell Communication and Signaling

Fig. 2

From: The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling

Fig. 2

Ewing sarcoma cell lines show chemotactic migration to plerixafor. a TC-32 and A673 cells were cultured in serum-free medium and migration to FBS (10%), CXCL12 (100 ng/ml) and plerixafor (1 μM) was analyzed after 48 h. Graphs represent means ± SD of three independent experiments performed in triplicates. b Plerixafor (0.1 μM) promotes wound healing in a confluent A673 monolayer grown in standard conditions, documented by bright field microscopy at 40× magnification. Numbers indicate percent wound gap as quantified by Image J software and MRI Wound Healing Tool. Photographs are representative of three independent experiments

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X