Fig. 9
From: miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT
miR-148b-3p suppresses the growth of GIST in vivo. (a) Representative images of subcutaneous tumors in mice receiving the miR-148b-3p agomir or the control (NC). (b) Tumor growth curves for the group of mice receiving miR-148b-3p agomir compared with the control group. (c) Tumor weights for mice with miR-148b-3p agomir injection compared to the control. (d) Representative Hematoxylin and eosin (HE) staining pictures of subcutaneous tumors for mice treated with miR-148b-3p or the NC. (e) Representative immunohistochemical staining of subcutaneous tumors for mice treated with miR-148b-3p or the NC. (f) Western blot analyses of phosphorylated and total ERK, AKT and STAT3 protein expression in subcutaneous tumors. *P<0.05, **P<0.01