Table 2 Up-regulated genes (FC ≥ 2) in TNF-α treated cells under normoxic and hypoxic conditions

NM_182920

ADAMTS9

ADAM metallopeptidase with thrombospondin type 1 motif, 9

15.34

25.45

3.05

10.59

NM_058172

ANTXR2

anthrax toxin receptor 2

2.64

4.43

3.61

5.63

NM_001165

BIRC3

baculoviral IAP repeat containing 3

4.55

13.11

23.74

97.65

NM_001734

C1S

complement component 1, s subcomponent

5.66

6.97

6.91

7.03

NM_000064

C3

complement component 3

4.31

4.24

182.13

115.58

NM_002982

CCL2

chemokine (C-C motif) ligand 2

25.36

39.20

179.73

62.92

NM_001252

CD70

CD70 molecule

3.15

6.99

4.76

4.52

NM_001710

CFB

complement factor B

2.41

2.28

11.21

5.74

NM_032888

COL27A1

collagen, type XXVII, alpha 1

2.70

4.45

2.09

5.29

NM_004405

DLX2

distal-less homeobox 2

2.39

7.50

5.38

4.42

NM_014888

FAM3C

family with sequence similarity 3. member C

2.08

2.50

3.27

4.06

NM_001024071

GCH1

GTP cyclohydrolase 1

2.20

3.07

2.93

3.83

NM_001300919

HMGA2

high mobility group AT-hook 2

2.26

2.35

3.27

3.66

NM_000201

ICAM1

intercellular adhesion molecule 1

4.46

6.91

5.76

3.58

NM_000873

ICAM2

intercellular adhesion molecule 2

2.53

4.04

4.71

46.87

NM_022377

ICAM4

intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

4.47

15.53

7.15

11.04

NM_003897

IER3

immediate early response 3

2.02

2.84

6.61

2.96

NM_022168

IFIH1

interferon induced with helicase C domain 1

2.43

3.47

2.01

2.48

NM_004843

IL27RA

interleukin 27 receptor. Alpha

2.65

2.31

3.47

2.56

NM_001012633

IL32

interleukin 32

4.47

4.23

45.05

61.04

NM_001012631

IL32

interleukin 32

3.53

5.65

174.41

103.38

NM_152899

IL4I1

interleukin 4 induced 1

13.76

46.63

50.44

74.89

NM_002185

IL7R

interleukin 7 receptor

2.81

3.65

23.52

8.37

NM_001570

IRAK2

interleukin-1 receptor-associated kinase 2

5.28

13.66

14.76

14.90

NM_004031

IRF7

interferon regulatory factor 7

2.30

2.31

4.20

2.17

NM_138433

KLHDC7B

kelch domain containing 7B

5.74

10.45

2.77

13.77

NM_001017402

LAMB3

laminin, beta 3

2.12

3.48

5.68

2.89

NM_005562

LAMC2

laminin, gamma 2

2.73

4.65

2.05

4.42

NM_015541

LRIG1

leucine-rich repeats and immunoglobulin-like domains 1

2.29

2.49

4.45

2.27

NM_004994

MMP9

matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)

11.45

27.25

13.49

44.92

NM_018406

MUC4

mucin 4, cell surface associated

2.49

4.72

2.34

2.76

NM_181782

NCOA7

nuclear receptor coactivator 7

2.08

2.89

2.14

3.31

NM_004289

NFE2L3

nuclear factor. Erythroid 2-like 3

3.08

7.27

5.00

8.99

NM_020529

NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

2.97

7.63

5.41

5.74

NM_004556

NFKBIE

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

3.86

4.40

3.41

3.14

NM_002526

NT5E

5′-nucleotidase, ecto (CD73)

4.37

9.64

7.12

3.26

NM_002526

NT5E

5′-nucleotidase, ecto (CD73)

3.37

8.28

3.62

2.54

NM_030952

NUAK2

NUAK family, SNF1-like kinase. 2

2.24

5.48

5.71

2.87

NM_001005377

PLAUR

plasminogen activator, urokinase receptor

4.00

2.12

14.94

2.74

NM_002852

PTX3

pentraxin 3, long

4.37

6.10

16.59

17.75

NM_006509

RELB

v-rel avian reticuloendotheliosis viral oncogene homolog B

5.02

8.99

4.61

4.41

NM_002960

S100A3

S100 calcium binding protein A3

2.01

2.88

4.90

7.84

NM_001002236

SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase. antitrypsin), member 1

2.50

2.73

5.44

2.35

NM_015482

SLC22A23

solute carrier family 22, member 23

2.08

2.23

3.21

7.09

NM_001024465

SOD2

superoxide dismutase 2, mitochondrial

2.48

5.20

16.52

19.28

NM_014220

TM4SF1

transmembrane 4 L six family member 1

2.08

3.23

5.34

3.43

NM_017870

TMEM132A

transmembrane protein 132A

2.63

3.35

3.74

3.53

NM_006290

TNFAIP3

tumor necrosis factor, alpha-induced protein 3

14.81

16.94

19.45

9.77

NM_145725

TRAF3

TNF receptor-associated factor 3

2.21

3.61

2.02

2.50

NM_006398

UBD

ubiquitin D

19.59

58.56

100.44

226.21

NM_005429

VEGFC

vascular endothelial growth factor C

2.76

4.16

74.91

33.90