Skip to main content
Fig. 1 | Cell Communication and Signaling

Fig. 1

From: The nuclear transportation routes of membrane-bound transcription factors

Fig. 1

The nuclear transportation routes of plasma membrane-bound proteins. (a1-a2) Some PM proteins are cleaved by regulated intramembrane proteolysis. The fragments facing to cytosol are released and relocated to the nucleus. (b1-b2) Some of them attach to the plasma membrane by palmitoylation. They release from the plasma membrane by depalmitoylation and then enter the nucleus upon signal induction. (c1-c5) Some proteins release from the membrane by endocytosis and then go to the Golgi. Through Golgi to ER retrograde trafficking, they are finally translocated into the nucleus

Back to article page