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Table 1 Comparison of baseline clinical characteristics based on HMGB2 expression level

From: HMGB2 is associated with malignancy and regulates Warburg effect by targeting LDHB and FBP1 in breast cancer

   

HMGB2

χ2 value

P value

Variable

 

n

Low (%)

High (%)

Age

    

0.140

0.904

≤55

86

34(45.9)

52(46.8)

  

> 55

99

40(54.1)

59(53.2)

  

Tumor Diameter

    

9.05

0.003

< 2 cm

73

39(52.7)

34(30.6)

  

≥2 cm

112

35(47.3)

77(69.4)

  

Grade

    

2.016

0.365

I

96

43(58.1)

53 (47.7)

  

II

70

25(33.8)

45(40.5)

  

III

19

6(8.1)

13(11.7)

  

Stage

    

6.801

0.033

I

26

12(16.2)

14(12.6)

  

II

75

37(50.0)

38(34.2)

  

III

84

25(9.8)

59(53.2)

  

Subtypes

    

4.733

0.129

Luminal A

88

40(54.1)

48(43.2)

  

Luminal B

42

13(17.6)

29(26.1)

  

Basal-like

33

10(13.5)

23(20.7)

  

Her-2+

22

11(14.9)

11(9.9)

  

ER Status

    

1.20

0.273

Negative

48

16(21.6)

32(28.8)

  

Positive

137

58(78.4)

79(71.2)

  

PR Status

    

2.183

0.140

Negative

72

24(32.7)

48(43.2)

  

Positive

113

50(67.6)

63(56.8)

  

HER-2/neu Status

    

0.498

0.480

Negative

152

59(79.7)

93(83.8)

  

Positive

33

15(20.3)

18(16.2)