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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway

Fig. 5

Effect of HQGGT in combination with 5-FU on MC38 tumor growth. HQGGT was orally administered QD × 5, and 5-FU was i.p. administered once a week for 6 weeks to MC38-bearing C57BL/6 mice. Tumor volume (a) and body weight (b) were determined twice a week. Measurements represent the mean ± SD (7 mice per group). **, p < 0.01 versus control; ##, p < 0.01 versus HQGGT alone. c Formalin-fixed sections of the liver and middle jejunum were stained with hematoxylin and eosin (H&E), Ki-67, and TUNEL after treatment with HQGGT. d IHC analysis for Ki-67 and TS staining was performed on formalin-fixed tumor sections. Scale bars are 100 μm

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Cell Communication and Signaling

ISSN: 1478-811X