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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer

Fig. 1

Expression Profiling of Hedgehog Pathway Members in Pakistani Cohort. a. Scatter plots showing mean relative mRNA expression of SHH, DHH, IHH, PTCH1, SMO and GLI1 in tumor samples as compared to normal tissues. b. Heatmap showing differential expression of analyzed molecules in tumors on left side and adjacent normal mammary tissues on right side. c. Immunostaining of SHH (A, B), DHH (C, D) and GLI1 (E, F) in normal tissues (A, C, E) and tumor tissues (B, D, F). (Wilcoxon Signed Rank Test, p < 0.0001)

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