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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model

Fig. 2

AMAP1 is expressed in cancer cells but not in stromal cells. Primary (a) or lung-metastasized (b) tumors from the PyMT (12–20 weeks old) or Neu (40–56 weeks old) mice, or mammary glands from wild-type (WT) mice (10 weeks old) were fixed, embedded in paraffin, and stained with an antibody to Arf6 or AMAP1. Normal mouse IgG (IgG) was used as a control for each staining. Nuclei were stained with hematoxylin. Representative images of each tumor are shown. Scale bar, 50 μm

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