Fig. 2From: Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer modelAMAP1 is expressed in cancer cells but not in stromal cells. Primary (a) or lung-metastasized (b) tumors from the PyMT (12–20 weeks old) or Neu (40–56 weeks old) mice, or mammary glands from wild-type (WT) mice (10 weeks old) were fixed, embedded in paraffin, and stained with an antibody to Arf6 or AMAP1. Normal mouse IgG (IgG) was used as a control for each staining. Nuclei were stained with hematoxylin. Representative images of each tumor are shown. Scale bar, 50 μmBack to article page