Fig. 6
From: Predictive model identifies strategies to enhance TSP1-mediated apoptosis signaling
Relationship between initial conditions and predicted apoptotic response. (a) Initial concentrations of PARP and XIAP for apoptotic cells (purple) and non-apoptotic cells (grey). The difference between the initial amounts of PARP and XIAP is larger for apoptotic cells, which reach higher cPARP levels. (b) Histogram showing distribution of initial XIAP concentration for apoptotic cells (purple) and non-apoptotic cells (grey). The apoptotic cells have relatively lower initial XIAP concentrations. (c) Histogram showing distribution of initial PARP concentrations for apoptotic cells (purple) and non-apoptotic cells (grey). The apoptotic cells have higher initial PARP concentrations