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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Adaptive phenotype drives resistance to androgen deprivation therapy in prostate cancer

Fig. 6

PCA of genes and proteins in LNCaP, MDB and PDB cell lines. a Three dimensional principal component sphere plots. Each sphere represents a technical replicate and the cell lines are associated to different colors. b Loading plot for the first principal component showing gene probes (left) and proteins (right) responsible for the clustering of samples. The scores were listed in descending order, having on the left the positive values and on the right the negative ones. The top genes (EPHA3, ETV1) and proteins (hnRNP U, RKIP) are indicated by arrows. In red the top ASPH gene/protein found in both datasets. c WB analysis of proteins from LNCaP, PDB and MDB. Expression level of the top five PCA gene/protein responsible for the maximal variation among data, was evaluated with antibodies to EPHA3, ETV1, hnRNP U, RKIP and ASPH

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