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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Crosstalk between glial and glioblastoma cells triggers the “go-or-grow” phenotype of tumor cells

Fig. 3

Quantitative comparison of specific secreted proteins from unprimed or primed glial cells, with putative paracrine effects in glioblastoma cells. a. Insulin-like growth factor-binding protein 2 (IBP-2); b. Metalloproteinase inhibitor 2 (TIMP-2); c. Fibronectin (FN); d. SPARC-like protein 1 and e. Myeloid-derived growth factor (MYDGF), were found to be upregulated in primed glial cells CM compared to unprimed CM. Values are shown as mean + SEM, n = 4. Statistical differences were calculated by paired Student’s t-test (*p < 0.05). IS, internal standard

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