TY - STD TI - Ostrom QT, Gittleman H, Fulop J, Liu M, Blanda R, Kromer C, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS: CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008–2012. Neuro-oncology 2015, 17:iv1-iv62. ID - ref1 ER - TY - JOUR AU - Koukourakis, G. V. AU - Kouloulias, V. AU - Zacharias, G. AU - Papadimitriou, C. AU - Pantelakos, P. AU - Maravelis, G. AU - Fotineas, A. AU - Beli, I. AU - Chaldeopoulos, D. AU - Kouvaris, J. PY - 2009 DA - 2009// TI - Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article JO - Molecules VL - 14 UR - https://doi.org/10.3390/molecules14041561 DO - 10.3390/molecules14041561 ID - Koukourakis2009 ER - TY - JOUR AU - Stupp, R. AU - Hegi, M. E. AU - Gilbert, M. R. AU - Chakravarti, A. PY - 2007 DA - 2007// TI - Chemoradiotherapy in malignant glioma: standard of care and future directions JO - J Clin Oncol VL - 25 UR - https://doi.org/10.1200/JCO.2007.11.8554 DO - 10.1200/JCO.2007.11.8554 ID - Stupp2007 ER - TY - JOUR AU - Patel, A. P. AU - Tirosh, I. AU - Trombetta, J. J. AU - Shalek, A. K. AU - Gillespie, S. M. AU - Wakimoto, H. AU - Cahill, D. P. AU - Nahed, B. V. AU - Curry, W. T. AU - Martuza, R. L. PY - 2014 DA - 2014// TI - Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma JO - Science VL - 344 UR - https://doi.org/10.1126/science.1254257 DO - 10.1126/science.1254257 ID - Patel2014 ER - TY - JOUR AU - Charles, N. A. AU - Holland, E. C. AU - Gilbertson, R. AU - Glass, R. AU - Kettenmann, H. PY - 2012 DA - 2012// TI - The brain tumor microenvironment JO - Glia VL - 60 UR - https://doi.org/10.1002/glia.21264 DO - 10.1002/glia.21264 ID - Charles2012 ER - TY - JOUR AU - Quail, D. F. AU - Bowman, R. L. AU - Akkari, L. AU - Quick, M. L. AU - Schuhmacher, A. J. AU - Huse, J. T. AU - Holland, E. C. AU - Sutton, J. C. AU - Joyce, J. A. PY - 2016 DA - 2016// TI - The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas JO - Science VL - 352 UR - https://doi.org/10.1126/science.aad3018 DO - 10.1126/science.aad3018 ID - Quail2016 ER - TY - JOUR AU - Hoelzinger, D. B. AU - Demuth, T. AU - Berens, M. E. PY - 2007 DA - 2007// TI - Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment JO - J Natl Cancer Inst VL - 99 UR - https://doi.org/10.1093/jnci/djm187 DO - 10.1093/jnci/djm187 ID - Hoelzinger2007 ER - TY - JOUR AU - Bonavia, R. AU - Cavenee, W. K. AU - Furnari, F. B. PY - 2011 DA - 2011// TI - Heterogeneity maintenance in glioblastoma: a social network JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-11-0153 DO - 10.1158/0008-5472.CAN-11-0153 ID - Bonavia2011 ER - TY - JOUR AU - Placone, A. L. AU - Quiñones-Hinojosa, A. AU - Searson, P. C. PY - 2016 DA - 2016// TI - The role of astrocytes in the progression of brain cancer: complicating the picture of the tumor microenvironment JO - Tumor Biol VL - 37 UR - https://doi.org/10.1007/s13277-015-4242-0 DO - 10.1007/s13277-015-4242-0 ID - Placone2016 ER - TY - JOUR AU - Rath, B. H. AU - Fair, J. M. AU - Jamal, M. AU - Camphausen, K. AU - Tofilon, P. J. PY - 2013 DA - 2013// TI - Astrocytes enhance the invasion potential of glioblastoma stem-like cells JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0054752 DO - 10.1371/journal.pone.0054752 ID - Rath2013 ER - TY - JOUR AU - Shabtay-Orbach, A. AU - Amit, M. AU - Binenbaum, Y. AU - Na'ara, S. AU - Gil, Z. PY - 2015 DA - 2015// TI - Paracrine regulation of glioma cells invasion by astrocytes is mediated by glial-derived neurotrophic factor JO - Int J Cancer VL - 137 UR - https://doi.org/10.1002/ijc.29380 DO - 10.1002/ijc.29380 ID - Shabtay-Orbach2015 ER - TY - JOUR AU - Zamanian, J. L. AU - Xu, L. AU - Foo, L. C. AU - Nouri, N. AU - Zhou, L. AU - Giffard, R. G. AU - Barres, B. A. PY - 2012 DA - 2012// TI - Genomic analysis of reactive astrogliosis JO - J Neurosci VL - 32 UR - https://doi.org/10.1523/JNEUROSCI.6221-11.2012 DO - 10.1523/JNEUROSCI.6221-11.2012 ID - Zamanian2012 ER - TY - JOUR AU - Roth, P. AU - Junker, M. AU - Tritschler, I. AU - Mittelbronn, M. AU - Dombrowski, Y. AU - Breit, S. N. AU - Tabatabai, G. AU - Wick, W. AU - Weller, M. AU - Wischhusen, J. PY - 2010 DA - 2010// TI - GDF-15 contributes to proliferation and immune escape of malignant gliomas JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-10-0705 DO - 10.1158/1078-0432.CCR-10-0705 ID - Roth2010 ER - TY - JOUR AU - Paltridge, J. L. AU - Belle, L. AU - Khew-Goodall, Y. PY - 2013 DA - 2013// TI - The secretome in cancer progression. Biochimica et Biophysica Acta (BBA)-Proteins and JO - Proteomics VL - 1834 ID - Paltridge2013 ER - TY - JOUR AU - Dowell, J. A. AU - Johnson, J. A. AU - Li, L. PY - 2009 DA - 2009// TI - Identification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics JO - J Proteome Res VL - 8 UR - https://doi.org/10.1021/pr900248y DO - 10.1021/pr900248y ID - Dowell2009 ER - TY - JOUR AU - Greco, T. M. AU - Seeholzer, S. H. AU - Mak, A. AU - Spruce, L. AU - Ischiropoulos, H. PY - 2010 DA - 2010// TI - Quantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretion JO - J Proteome Res VL - 9 UR - https://doi.org/10.1021/pr100134n DO - 10.1021/pr100134n ID - Greco2010 ER - TY - JOUR AU - Han, D. AU - Jin, J. AU - Woo, J. AU - Min, H. AU - Kim, Y. PY - 2014 DA - 2014// TI - Proteomic analysis of mouse astrocytes and their secretome by a combination of FASP and StageTip-based, high pH, reversed-phase fractionation JO - Proteomics VL - 14 UR - https://doi.org/10.1002/pmic.201300495 DO - 10.1002/pmic.201300495 ID - Han2014 ER - TY - STD TI - Anjo SI, Lourenço AS, Melo MN, Santa C, Manadas B. Unraveling Mesenchymal Stem Cells’ Dynamic Secretome Through Nontargeted Proteomics Profiling. Mesenchymal Stem Cells: Methods and Protocols. 2016:521–49. ID - ref18 ER - TY - JOUR AU - Manadas, B. J. AU - Vougas, K. AU - Fountoulakis, M. AU - Duarte, C. B. PY - 2006 DA - 2006// TI - Sample sonication after trichloroacetic acid precipitation increases protein recovery from cultured hippocampal neurons, and improves resolution and reproducibility in two-dimensional gel electrophoresis JO - Electrophoresis VL - 27 UR - https://doi.org/10.1002/elps.200500757 DO - 10.1002/elps.200500757 ID - Manadas2006 ER - TY - JOUR AU - Anjo, S. I. AU - Santa, C. AU - Manadas, B. PY - 2015 DA - 2015// TI - Short GeLC-SWATH: A fast and reliable quantitative approach for proteomic screenings JO - Proteomics VL - 15 UR - https://doi.org/10.1002/pmic.201400221 DO - 10.1002/pmic.201400221 ID - Anjo2015 ER - TY - JOUR AU - Tang, W. H. AU - Shilov, I. V. AU - Seymour, S. L. PY - 2008 DA - 2008// TI - Nonlinear fitting method for determining local false discovery rates from decoy database searches JO - J Proteome Res VL - 7 UR - https://doi.org/10.1021/pr070492f DO - 10.1021/pr070492f ID - Tang2008 ER - TY - JOUR AU - Sennels, L. AU - Bukowski-Wills, J. -. C. AU - Rappsilber, J. PY - 2009 DA - 2009// TI - Improved results in proteomics by use of local and peptide-class specific false discovery rates JO - BMC Bioinformatics VL - 10 UR - https://doi.org/10.1186/1471-2105-10-179 DO - 10.1186/1471-2105-10-179 ID - Sennels2009 ER - TY - STD TI - Gillet LC, Navarro P, Tate S, Röst H, Selevsek N, Reiter L, Bonner R, Aebersold R: Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis. Molecular & Cellular Proteomics 2012, 11:(6)O111. 016717. ID - ref23 ER - TY - JOUR AU - Collins, B. C. AU - Gillet, L. C. AU - Rosenberger, G. AU - Röst, H. L. AU - Vichalkovski, A. AU - Gstaiger, M. AU - Aebersold, R. PY - 2013 DA - 2013// TI - Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2703 DO - 10.1038/nmeth.2703 ID - Collins2013 ER - TY - JOUR AU - Vizcaíno, J. A. AU - Deutsch, E. W. AU - Wang, R. AU - Csordas, A. AU - Reisinger, F. AU - Rios, D. AU - Dianes, J. A. AU - Sun, Z. AU - Farrah, T. AU - Bandeira, N. PY - 2014 DA - 2014// TI - ProteomeXchange provides globally coordinated proteomics data submission and dissemination JO - Nat Biotechnol VL - 32 UR - https://doi.org/10.1038/nbt.2839 DO - 10.1038/nbt.2839 ID - Vizcaíno2014 ER - TY - JOUR AU - Coppé, J. -. P. AU - Desprez, P. -. Y. AU - Krtolica, A. AU - Campisi, J. PY - 2010 DA - 2010// TI - The senescence-associated secretory phenotype: the dark side of tumor suppression JO - Annual Review of Pathological Mechanical Disease VL - 5 UR - https://doi.org/10.1146/annurev-pathol-121808-102144 DO - 10.1146/annurev-pathol-121808-102144 ID - Coppé2010 ER - TY - JOUR AU - Munoz-Espin, D. AU - Serrano, M. PY - 2014 DA - 2014// TI - Cellular senescence: from physiology to pathology JO - Nat Rev Mol Cell Biol VL - 15 UR - https://doi.org/10.1038/nrm3823 DO - 10.1038/nrm3823 ID - Munoz-Espin2014 ER - TY - JOUR AU - Wagner, J. AU - Damaschke, N. AU - Yang, B. AU - Truong, M. AU - Guenther, C. AU - McCormick, J. AU - Huang, W. AU - Jarrard, D. PY - 2015 DA - 2015// TI - Overexpression of the novel senescence marker β-galactosidase (GLB1) in prostate cancer predicts reduced PSA recurrence JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0124366 DO - 10.1371/journal.pone.0124366 ID - Wagner2015 ER - TY - JOUR AU - Lee, B. Y. AU - Han, J. A. AU - Im, J. S. AU - Morrone, A. AU - Johung, K. AU - Goodwin, E. C. AU - Kleijer, W. J. AU - DiMaio, D. AU - Hwang, E. S. PY - 2006 DA - 2006// TI - Senescence-associated β-galactosidase is lysosomal β-galactosidase JO - Aging Cell VL - 5 UR - https://doi.org/10.1111/j.1474-9726.2006.00199.x DO - 10.1111/j.1474-9726.2006.00199.x ID - Lee2006 ER - TY - JOUR AU - Ewald, J. A. AU - Desotelle, J. A. AU - Wilding, G. AU - Jarrard, D. F. PY - 2010 DA - 2010// TI - Therapy-induced senescence in cancer JO - JNCI: Journal of the National Cancer Institute VL - 102 UR - https://doi.org/10.1093/jnci/djq364 DO - 10.1093/jnci/djq364 ID - Ewald2010 ER - TY - JOUR AU - Wagner, E. F. AU - Nebreda, Á. R. PY - 2009 DA - 2009// TI - Signal integration by JNK and p38 MAPK pathways in cancer development JO - Nat Rev Cancer VL - 9 UR - https://doi.org/10.1038/nrc2694 DO - 10.1038/nrc2694 ID - Wagner2009 ER - TY - JOUR AU - De Luca, A. AU - Maiello, M. R. AU - D'Alessio, A. AU - Pergameno, M. AU - Normanno, N. PY - 2012 DA - 2012// TI - The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches JO - Expert Opin Ther Targets VL - 16 UR - https://doi.org/10.1517/14728222.2011.639361 DO - 10.1517/14728222.2011.639361 ID - De Luca2012 ER - TY - JOUR AU - Dreesen, O. AU - Brivanlou, A. H. PY - 2007 DA - 2007// TI - Signaling pathways in cancer and embryonic stem cells JO - Stem Cell Rev VL - 3 UR - https://doi.org/10.1007/s12015-007-0004-8 DO - 10.1007/s12015-007-0004-8 ID - Dreesen2007 ER - TY - JOUR AU - Kim, S. -. J. AU - Kim, J. -. S. AU - Park, E. S. AU - Lee, J. -. S. AU - Lin, Q. AU - Langley, R. R. AU - Maya, M. AU - He, J. AU - Kim, S. -. W. AU - Weihua, Z. PY - 2011 DA - 2011// TI - Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy JO - Neoplasia VL - 13 UR - https://doi.org/10.1593/neo.11112 DO - 10.1593/neo.11112 ID - Kim2011 ER - TY - STD TI - Jha MK, Seo M, Kim J-H, Kim BG, Cho JY, Suk K: The secretome signature of reactive glial cells and its pathological implications. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 2013, 1834:2418–2428. ID - ref35 ER - TY - JOUR AU - Keene, S. D. AU - Greco, T. M. AU - Parastatidis, I. AU - Lee, S. H. AU - Hughes, E. G. AU - Balice-Gordon, R. J. AU - Speicher, D. W. AU - Ischiropoulos, H. PY - 2009 DA - 2009// TI - Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome JO - Proteomics VL - 9 UR - https://doi.org/10.1002/pmic.200800385 DO - 10.1002/pmic.200800385 ID - Keene2009 ER - TY - JOUR AU - Brown, K. J. AU - Seol, H. AU - Pillai, D. K. AU - Sankoorikal, B. -. J. AU - Formolo, C. A. AU - Mac, J. AU - Edwards, N. J. AU - Rose, M. C. AU - Hathout, Y. PY - 2013 DA - 2013// TI - The human secretome atlas initiative: implications in health and disease conditions. Biochimica et Biophysica Acta (BBA)-Proteins and JO - Proteomics VL - 1834 ID - Brown2013 ER - TY - JOUR AU - Choi, S. S. AU - Lee, H. J. AU - Lim, I. AU - Satoh, J. -. i. AU - Kim, S. U. PY - 2014 DA - 2014// TI - Human astrocytes: secretome profiles of cytokines and chemokines JO - PloS one VL - 9 UR - https://doi.org/10.1371/journal.pone.0092325 DO - 10.1371/journal.pone.0092325 ID - Choi2014 ER - TY - JOUR AU - Oh, T. AU - Fakurnejad, S. AU - Sayegh, E. T. AU - Clark, A. J. AU - Ivan, M. E. AU - Sun, M. Z. AU - Safaee, M. AU - Bloch, O. AU - James, C. D. AU - Parsa, A. T. PY - 2014 DA - 2014// TI - Immunocompetent murine models for the study of glioblastoma immunotherapy JO - J Transl Med VL - 12 UR - https://doi.org/10.1186/1479-5876-12-107 DO - 10.1186/1479-5876-12-107 ID - Oh2014 ER - TY - JOUR AU - Pekny, M. AU - Pekna, M. PY - 2014 DA - 2014// TI - Astrocyte reactivity and reactive astrogliosis: costs and benefits JO - Physiol Rev VL - 94 UR - https://doi.org/10.1152/physrev.00041.2013 DO - 10.1152/physrev.00041.2013 ID - Pekny2014 ER - TY - JOUR AU - Okolie, O. AU - Bago, J. R. AU - Schmid, R. S. AU - Irvin, D. M. AU - Bash, R. E. AU - Miller, C. R. AU - Hingtgen, S. D. PY - 2016 DA - 2016// TI - Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model JO - Neuro-Oncology VL - 18 UR - https://doi.org/10.1093/neuonc/now117 DO - 10.1093/neuonc/now117 ID - Okolie2016 ER - TY - JOUR AU - Giese, A. AU - Loo, M. A. AU - Tran, N. AU - Haskett, D. AU - Coons, S. W. AU - Berens, M. E. PY - 1996 DA - 1996// TI - Dichotomy of astrocytoma migration and proliferation JO - Int J Cancer VL - 67 UR - https://doi.org/3.0.CO;2-9 DO - 3.0.CO;2-9 ID - Giese1996 ER - TY - JOUR AU - Hatzikirou, H. AU - Basanta, D. AU - Simon, M. AU - Schaller, K. AU - Deutsch, A. PY - 2010 DA - 2010// TI - ‘Go or Grow’: the key to the emergence of invasion in tumour progression? JO - Math Med Biol VL - 29 UR - https://doi.org/10.1093/imammb/dqq011 DO - 10.1093/imammb/dqq011 ID - Hatzikirou2010 ER - TY - JOUR AU - Giese, A. AU - Bjerkvig, R. AU - Berens, M. AU - Westphal, M. PY - 2003 DA - 2003// TI - Cost of migration: invasion of malignant gliomas and implications for treatment JO - J Clin Oncol VL - 21 UR - https://doi.org/10.1200/JCO.2003.05.063 DO - 10.1200/JCO.2003.05.063 ID - Giese2003 ER - TY - JOUR AU - Han, S. AU - Li, Z. AU - Master, L. AU - Master, Z. AU - Wu, A. PY - 2014 DA - 2014// TI - Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway JO - Br J Cancer VL - 111 UR - https://doi.org/10.1038/bjc.2014.435 DO - 10.1038/bjc.2014.435 ID - Han2014 ER - TY - JOUR AU - Korf-Klingebiel, M. AU - Reboll, M. R. AU - Klede, S. AU - Brod, T. AU - Pich, A. AU - Polten, F. AU - Napp, L. C. AU - Bauersachs, J. AU - Ganser, A. AU - Brinkmann, E. PY - 2015 DA - 2015// TI - Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction JO - Nat Med VL - 21 UR - https://doi.org/10.1038/nm.3778 DO - 10.1038/nm.3778 ID - Korf-Klingebiel2015 ER - TY - JOUR AU - Sunagozaka, H. AU - Honda, M. AU - Yamashita, T. AU - Nishino, R. AU - Takatori, H. AU - Arai, K. AU - Yamashita, T. AU - Sakai, Y. AU - Kaneko, S. PY - 2011 DA - 2011// TI - Identification of a secretory protein c19orf10 activated in hepatocellular carcinoma JO - Int J Cancer VL - 129 UR - https://doi.org/10.1002/ijc.25830 DO - 10.1002/ijc.25830 ID - Sunagozaka2011 ER - TY - JOUR AU - Danen, E. H. AU - Yamada, K. M. PY - 2001 DA - 2001// TI - Fibronectin, integrins, and growth control JO - J Cell Physiol VL - 189 UR - https://doi.org/10.1002/jcp.1137 DO - 10.1002/jcp.1137 ID - Danen2001 ER - TY - JOUR AU - Matsuo, M. AU - Sakurai, H. AU - Ueno, Y. AU - Ohtani, O. AU - Saiki, I. PY - 2006 DA - 2006// TI - Activation of MEK/ERK and PI3K/Akt pathways by fibronectin requires integrin αv-mediated ADAM activity in hepatocellular carcinoma: A novel functional target for gefitinib JO - Cancer Sci VL - 97 UR - https://doi.org/10.1111/j.1349-7006.2006.00152.x DO - 10.1111/j.1349-7006.2006.00152.x ID - Matsuo2006 ER - TY - JOUR AU - Esposito, I. AU - Kayed, H. AU - Keleg, S. AU - Giese, T. AU - Sage, E. H. AU - Schirmacher, P. AU - Friess, H. AU - Kleeff, J. PY - 2007 DA - 2007// TI - Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer JO - Neoplasia VL - 9 UR - https://doi.org/10.1593/neo.06646 DO - 10.1593/neo.06646 ID - Esposito2007 ER - TY - JOUR AU - Valente, P. AU - Fassina, G. AU - Melchiori, A. AU - Masiello, L. AU - Cilli, M. AU - Vacca, A. AU - Onisto, M. AU - Santi, L. AU - Stetler-Stevenson, W. G. AU - Albini, A. PY - 1998 DA - 1998// TI - TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis JO - Int J Cancer VL - 75 UR - https://doi.org/3.0.CO;2-B DO - 3.0.CO;2-B ID - Valente1998 ER - TY - JOUR AU - Clarke, M. R. AU - Imhoff, F. M. AU - Baird, S. K. PY - 2015 DA - 2015// TI - Mesenchymal stem cells inhibit breast cancer cell migration and invasion through secretion of tissue inhibitor of metalloproteinase-1 and-2 JO - Mol Carcinog VL - 54 UR - https://doi.org/10.1002/mc.22178 DO - 10.1002/mc.22178 ID - Clarke2015 ER - TY - JOUR AU - Li, X. AU - Wu, C. AU - Chen, N. AU - Gu, H. AU - Yen, A. AU - Cao, L. AU - Wang, E. AU - Wang, L. PY - 2016 DA - 2016// TI - PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma JO - Oncotarget VL - 7 UR - https://doi.org/10.18632/oncotarget.7961 DO - 10.18632/oncotarget.7961 ID - Li2016 ER -