Fig. 4From: CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathwayIncreased expression level of CLCA1 suppresses CRC cell colony formation ability in vitro. a Images of the colony formation assay with CLCA1-ACT and CLCA1-ACT-NC cells. b The mean number of colonies in CLCA1-ACT and CLCA1-ACT-NC cells (PÂ <Â 0.0001Â t-test). c Images of the colony formation assay with CLCA1-KO and CLCA1-KO-NC cells. d Mean number of colonies in the CLCA1-KO and CLCA1-KO-NC cells (PÂ <Â 0.0001, t-test). Abbreviations: CLCA1-ACT, CLCA1-upregulated cells; CLCA1-ACT-NC, negative control of CLCA1-upregulated cells; CLCA1-KO, CLCA1-knockout cells; CLCA1-KO-NC, negative control of CLCA1-knockout cellsBack to article page