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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line

Fig. 5

MCF-7 cells treated with IL6 and IL8 exhibit self-renewal properties. a Sphere formation assay in the presence of defined medium (EGF and FGF) in MCF-7 cells that were previously treated or not (Control) with SCM (a and b) or with cytokines (c and d) during 5 days. Representative micrographs (10×) show sphere formation after 8 days of induction. Scale bar, 100 μm. The total number of spheres per well larger than 100 μm was counted at day 8. Error bars indicate SEM. (**p < 0.01) (n = 2)

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Cell Communication and Signaling

ISSN: 1478-811X