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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin

Fig. 3

Treatment of HCT116 cells with 5-FU or oxaliplatin results in decreased TCTP mRNA levels. HCT116 cells were treated with 5-FU (20 μM) or oxaliplatin (12.5 μM) or culture medium (control) for 48 h (n = 4). TCTP mRNA levels were assessed by RT-qPCR and normalised against β2-tubulin mRNA as reference. Values are presented as mean percentage expression change, compared to untreated control cells ± SEM (***P < 0.001 vs. control)

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