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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin

Fig. 1

TCTP protein levels increase significantly in the early stages of human colon cancer development. a Immunohistochemical staining with an anti-TCTP antibody of paraffin-embedded tumour samples from colon cancer patients with confirmed adenomas (C , D), non-metastatic (E, F) or metastatic adenocarcinomas (G, H). Areas from surrounding normal colon were used as a control (A, B). Representative examples are shown for each group at 80 × and 400 × magnification. b Graph showing the average TCTP scoring for each patient group, normalised to TCTP levels in normal colon tissue (*P = 0.052; **P = 0.001; ***P < 0.001). c Graph representing the score distribution for each patient group (see Methods for scoring)

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