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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28

Fig. 6

CXCR4 surface expression in infected HUVEC. At 24 and 96 hours post infection (hpi), mock- and TB40E/IE2eYFP- (wt) or TB40E/IE2eYFP-delUS28- (ΔUS28) infected HUVEC were examined by FACS for surface expression of CXCR4. Fluorescently labeled IE2-eYFP enabled detection of CXCR4 surface expression in lytically-infected cells only. The percentages of HUVEC expressing CXCR4 were evaluated in mock- or lytically-infected (IE2-positive) cells at 24 hpi (a) or 96 hpi (b). Values are the mean ± SD of three experiments

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Cell Communication and Signaling

ISSN: 1478-811X