Fig. 3From: Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancerModulation of IRS1 and IRS2 expression in human MCF10A breast cells alters ErbB2 signaling. MCF10A cells stably overexpressing HA-IRS1 or HA-IRS2 were serum starved for 24 h and then treated with 20 ng/ul heregulin (H) or 60 ng/ul EGF (E) for 15 mins and harvested. Immunoblotting was performed to determine ErbB2 signalingBack to article page