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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: The new (dis)order in RNA regulation

Fig. 2

Structural examples RNA-bound disordered regions. a The RGG-peptide of the human FMRP bound to a in vitro-selected guanine-rich sc1 RNA determined by NMR (PDB 2LA5) [78] b Basic patch of disordered bovine immunodeficiency virus (BIV) Tat forms a β–turn when interacting with its target RNA, TAR. Structure determined by NMR (PDB 1MNB) [91] c Dimer of the basic patch containing Rev protein of the human immunodeficiency virus (HIV) in complex with target RNA, RRE, determined by crystallography [102] (PDB 4PMI). Red, peptide; yellow, RNA. Illustrations were created using PyMol

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