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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Motif mediated protein-protein interactions as drug targets

Fig. 1

Classification of protein–protein interaction types based on affinity and stability. Stable complex (PDB: 1 F34) Structure of Ascaris pepsin inhibitor-3 bound to Porcine pepsin; Transient Domain-Domain interaction (PDB: 1AY7) Structure of the Ribonuclease SA Complex With Barstar; Transient Domain-Motif interaction (PDB: 1YCR) Structure of the MDM2 oncoprotein bound to the p53 tumour suppressor. For each complex, one of the interacting partners is displayed in blue cartoon representation, while the other is displayed in grey surface representation with the interface highlighted in red

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