Fig. 1From: Vps34 and PLD1 take center stage in nutrient signaling: their dual roles in regulating autophagyThe process of autophagy. a Under nutrient deficient condition, ULK1 complex (ULK1-FIP200-ATG13) is activated and translocated to a particular area of the ER. Then , ULK1 activates Vps34 complex (Vps34-Vps15-Beclin1-Atg14L) to produce PI(3)P. b The ATG12-ATG5-ATG16L complex is crucial for formation of the covalent bond between LC3B and phosphatidylethanolamine (PE)Back to article page