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Table 2 Rule of thumb quality scoring scheme

From: Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad

Score

Evidence

−1

Contradictory evidence

0

No evidence

1

Indirect supporting evidence

2

Direct supporting evidence for binding but not for in-cell function

2

Evidence in-cell that proteins associate, but direct supporting evidence for motif binding in vitro is lacking

3

Direct supporting evidence for both binding and in-cell function