Fig. 2

Linear Motifs in T cell receptor signalling pathway hsa04660. “T cell receptor signaling pathway” obtained from KEGG [83] and redrawn using Cytoscape [84] and KEGGScape [85]. Colour coding illustrates the use of linear motifs according to instances annotated in ELM [26] as follows: docking motifs in blue; degradation motifs (degrons) in yellow; ligand-binding motifs in green; sites for post-translational modification in pink; and targeting/trafficking motifs in orange. Note that only motif interactions annotated in the ELM resource have been considered for colouring: Other functionality is not coloured