Cell Communication and Signaling

Table 2 Table of several classical SLiM-binding domain families, and representative DNA and RNA motif-binding domain families^a

From: Short linear motifs – ex nihilo evolution of protein regulation

Domain type	Domain	Ath	Ddi	Sce	Dme	Hsa
SLiM-binding	SH3 domain	5	29	23	59	204
	PDZ domain	17	1	2	67	145
	SH2 domain	2	13	0	32	110
	WW domain	9	5	6	21	41
	Kinase domain	1066	309	132	289	523
DNA-binding	C2H2/C2HC zinc finger	22	6	34	197	659
RNA-binding	RRM domain	268	96	58	137	265

^aThe number of instances of each family in Arabidopsis thaliana (Ath), Dictyostelium discoideum (Ddi), Saccharomyces cerevisiae (Sce), Drosophila melanogaster (Dme), Homo sapiens (Hsa). Data from Vogel et al. [95]

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ISSN: 1478-811X

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