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Table 2 Table of several classical SLiM-binding domain families, and representative DNA and RNA motif-binding domain familiesa

From: Short linear motifs – ex nihilo evolution of protein regulation

Domain type Domain Ath Ddi Sce Dme Hsa
SLiM-binding SH3 domain 5 29 23 59 204
PDZ domain 17 1 2 67 145
SH2 domain 2 13 0 32 110
WW domain 9 5 6 21 41
Kinase domain 1066 309 132 289 523
DNA-binding C2H2/C2HC zinc finger 22 6 34 197 659
RNA-binding RRM domain 268 96 58 137 265
  1. aThe number of instances of each family in Arabidopsis thaliana (Ath), Dictyostelium discoideum (Ddi), Saccharomyces cerevisiae (Sce), Drosophila melanogaster (Dme), Homo sapiens (Hsa). Data from Vogel et al. [95]