TY - JOUR AU - Birge, R. B. AU - Kalodimos, C. AU - Inagaki, F. AU - Tanaka, S. PY - 2009 DA - 2009// TI - Crk and CrkL adaptor proteins: networks for physiological and pathological signaling JO - Cell Commun Signal VL - 7 UR - https://doi.org/10.1186/1478-811X-7-13 DO - 10.1186/1478-811X-7-13 ID - Birge2009 ER - TY - JOUR AU - Kobashigawa, Y. AU - Sakai, M. AU - Naito, M. AU - Yokochi, M. AU - Kumeta, H. AU - Makino, Y. PY - 2007 DA - 2007// TI - Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK JO - Nat Struct Mol Biol VL - 14 UR - https://doi.org/10.1038/nsmb1241 DO - 10.1038/nsmb1241 ID - Kobashigawa2007 ER - TY - JOUR AU - Brugnera, E. AU - Haney, L. AU - Grimsley, C. AU - Lu, M. AU - Walk, S. F. AU - Tosello-Trampont, A. C. PY - 2002 DA - 2002// TI - Unconventional Rac-GEF activity is mediated through the Dock180 ELMO complex JO - Nat Cell Biol VL - 4 ID - Brugnera2002 ER - TY - JOUR AU - Gumienny, T. L. AU - Brugnera, E. AU - Tosello-Trampont, A. C. AU - Kinchen, J. M. AU - Haney, L. B. AU - Nishiwaki, K. PY - 2001 DA - 2001// TI - CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration JO - Cell VL - 107 UR - https://doi.org/10.1016/S0092-8674(01)00520-7 DO - 10.1016/S0092-8674(01)00520-7 ID - Gumienny2001 ER - TY - JOUR AU - Zhou, Z. AU - Caron, E. AU - Hartwieg, E. AU - Hall, A. AU - Horvitz, H. R. PY - 2001 DA - 2001// TI - The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway JO - Dev Cell VL - 1 UR - https://doi.org/10.1016/S1534-5807(01)00058-2 DO - 10.1016/S1534-5807(01)00058-2 ID - Zhou2001 ER - TY - JOUR AU - Lu, M. AU - Kinchen, J. M. AU - Rossman, K. L. AU - Grimsley, C. AU - Hall, M. AU - Sondek, J. PY - 2005 DA - 2005// TI - A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs JO - Curr Biol VL - 15 UR - https://doi.org/10.1016/j.cub.2005.01.050 DO - 10.1016/j.cub.2005.01.050 ID - Lu2005 ER - TY - JOUR AU - Komander, D. AU - Patel, M. AU - Laurin, M. AU - Fradet, N. AU - Pelletier, A. AU - Barford, D. PY - 2008 DA - 2008// TI - An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling JO - Mol Biol Cell VL - 19 UR - https://doi.org/10.1091/mbc.E08-04-0345 DO - 10.1091/mbc.E08-04-0345 ID - Komander2008 ER - TY - JOUR AU - deBakker, C. D. AU - Haney, L. B. AU - Kinchen, J. M. AU - Grimsley, C. AU - Lu, M. AU - Klingele, D. PY - 2004 DA - 2004// TI - Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO JO - Curr Biol VL - 14 UR - https://doi.org/10.1016/j.cub.2004.12.029 DO - 10.1016/j.cub.2004.12.029 ID - deBakker2004 ER - TY - JOUR AU - Katoh, H. AU - Negishi, M. PY - 2003 DA - 2003// TI - RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo JO - Nature VL - 424 UR - https://doi.org/10.1038/nature01817 DO - 10.1038/nature01817 ID - Katoh2003 ER - TY - JOUR AU - Shimazaki, A. AU - Kawamura, Y. AU - Kanazawa, A. AU - Sekine, A. AU - Saito, S. AU - Tsunoda, T. PY - 2005 DA - 2005// TI - Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy JO - Diabetes VL - 54 UR - https://doi.org/10.2337/diabetes.54.4.1171 DO - 10.2337/diabetes.54.4.1171 ID - Shimazaki2005 ER - TY - JOUR AU - Janardhan, A. AU - Swigut, T. AU - Hill, B. AU - Myers, M. P. AU - Skowronski, J. PY - 2004 DA - 2004// TI - HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis JO - PLoS Biol VL - 2 UR - https://doi.org/10.1371/journal.pbio.0020006 DO - 10.1371/journal.pbio.0020006 ID - Janardhan2004 ER - TY - JOUR AU - Jarzynka, M. J. AU - Hu, B. AU - Hui, K. M. AU - Bar-Joseph, I. AU - Gu, W. AU - Hirose, T. PY - 2007 DA - 2007// TI - ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-07-0473 DO - 10.1158/0008-5472.CAN-07-0473 ID - Jarzynka2007 ER - TY - JOUR AU - Wang, H. AU - Linghu, H. AU - Wang, J. AU - Che, Y. L. AU - Xiang, T. X. AU - Tang, W. X. PY - 2010 DA - 2010// TI - The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3 JO - Tumour Biol VL - 31 UR - https://doi.org/10.1007/s13277-009-0009-9 DO - 10.1007/s13277-009-0009-9 ID - Wang2010 ER - TY - JOUR AU - Makino, Y. AU - Tsuda, M. AU - Ichihara, S. AU - Watanabe, T. AU - Sakai, M. AU - Sawa, H. PY - 2006 DA - 2006// TI - Elmo1 inhibits ubiquitylation of Dock180 JO - J Cell Sci VL - 119 UR - https://doi.org/10.1242/jcs.02797 DO - 10.1242/jcs.02797 ID - Makino2006 ER - TY - JOUR AU - Yokoyama, N. AU - deBakker, C. D. AU - Zappacosta, F. AU - Huddleston, M. J. AU - Annan, R. S. AU - Ravichandran, K. S. PY - 2005 DA - 2005// TI - Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck JO - Biochemistry VL - 44 UR - https://doi.org/10.1021/bi0500832 DO - 10.1021/bi0500832 ID - Yokoyama2005 ER - TY - JOUR AU - Awad, R. AU - Sévajol, M. AU - Ayala, I. AU - Chouquet, A. AU - Frachet, P. AU - Gans, P. PY - 2015 DA - 2015// TI - The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif JO - FEBS Open Bio VL - 5 UR - https://doi.org/10.1016/j.fob.2015.01.009 DO - 10.1016/j.fob.2015.01.009 ID - Awad2015 ER - TY - JOUR AU - Abu-Thuraia, A. AU - Gauthier, R. AU - Chidiac, R. AU - Fukui, Y. AU - Screaton, R. A. AU - Gratton, J. P. PY - 2015 DA - 2015// TI - Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion JO - Mol Cell Biol VL - 35 UR - https://doi.org/10.1128/MCB.00764-14 DO - 10.1128/MCB.00764-14 ID - Abu-Thuraia2015 ER - TY - JOUR AU - Summy, J. M. AU - Gallick, G. E. PY - 2003 DA - 2003// TI - Src family kinases in tumor progression and metastasis JO - Cancer Metastasis Rev VL - 22 UR - https://doi.org/10.1023/A:1023772912750 DO - 10.1023/A:1023772912750 ID - Summy2003 ER - TY - JOUR AU - Yeatman, T. J. PY - 2004 DA - 2004// TI - A renaissance for SRC JO - Nat Rev Cancer VL - 4 UR - https://doi.org/10.1038/nrc1366 DO - 10.1038/nrc1366 ID - Yeatman2004 ER - TY - JOUR AU - Laird, A. D. AU - Li, G. AU - Moss, K. G. AU - Blake, R. A. AU - Broome, M. A. AU - Cherrington, J. M. PY - 2003 DA - 2003// TI - Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells JO - Mol Cancer Ther VL - 2 ID - Laird2003 ER - TY - JOUR AU - Irby, R. B. AU - Yeatman, T. J. PY - 2000 DA - 2000// TI - Role of Src expression and activation in human cancer JO - Oncogene VL - 19 UR - https://doi.org/10.1038/sj.onc.1203912 DO - 10.1038/sj.onc.1203912 ID - Irby2000 ER - TY - JOUR AU - Guarino, M. PY - 2010 DA - 2010// TI - Src signaling in cancer invasion JO - J Cell Physiol VL - 223 ID - Guarino2010 ER - TY - JOUR AU - Grimsley, C. M. AU - Lu, M. AU - Haney, L. B. AU - Kinchen, J. M. AU - Ravichandran, K. S. PY - 2006 DA - 2006// TI - Characterization of a novel interaction between ELMO1 and ERM proteins JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M510647200 DO - 10.1074/jbc.M510647200 ID - Grimsley2006 ER - TY - JOUR AU - Liang, W. AU - Kujawski, M. AU - Wu, J. AU - Lu, J. AU - Herrmann, A. AU - Loera, S. PY - 2010 DA - 2010// TI - Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-1486 DO - 10.1158/1078-0432.CCR-09-1486 ID - Liang2010 ER - TY - JOUR AU - Albert, M. L. AU - Kim, J. -. I. AU - Birge, R. B. PY - 2000 DA - 2000// TI - avb5 integrin recruits the CrkII-Dock180-Rac1 complex for phagocytosis of apoptotic cells JO - Nature Cell Biol VL - 2 UR - https://doi.org/10.1038/35046549 DO - 10.1038/35046549 ID - Albert2000 ER - TY - JOUR AU - Gustavsson, A. AU - Yuan, M. AU - Fallman, M. PY - 2004 DA - 2004// TI - Temporal dissection of beta1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M309693200 DO - 10.1074/jbc.M309693200 ID - Gustavsson2004 ER - TY - JOUR AU - Wu, Y. AU - Singh, S. AU - Georgescu, M. M. AU - Birge, R. B. PY - 2005 DA - 2005// TI - A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells JO - J Cell Sci VL - 118 UR - https://doi.org/10.1242/jcs.01632 DO - 10.1242/jcs.01632 ID - Wu2005 ER - TY - JOUR AU - Ouyang, M. AU - Sun, J. AU - Chien, S. AU - Wang, Y. PY - 2008 DA - 2008// TI - Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0807537105 DO - 10.1073/pnas.0807537105 ID - Ouyang2008 ER - TY - JOUR AU - Meller, J. AU - Vidali, L. AU - Schwartz, M. A. PY - 2008 DA - 2008// TI - Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration JO - J Cell Sci VL - 121 UR - https://doi.org/10.1242/jcs.025130 DO - 10.1242/jcs.025130 ID - Meller2008 ER - TY - JOUR AU - Katoh, H. AU - Hiramoto, K. AU - Negishi, M. PY - 2006 DA - 2006// TI - Activation of Rac1 by RhoG regulates cell migration JO - J Cell Sci VL - 119 UR - https://doi.org/10.1242/jcs.02720 DO - 10.1242/jcs.02720 ID - Katoh2006 ER - TY - JOUR AU - Mayer, E. L. AU - Krop, I. E. PY - 2010 DA - 2010// TI - Advances in targeting SRC in the treatment of breast cancer and other solid malignancies JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-1834 DO - 10.1158/1078-0432.CCR-09-1834 ID - Mayer2010 ER - TY - JOUR AU - Epting, D. AU - Wendik, B. AU - Bennewitz, K. AU - Dietz, C. T. AU - Driever, W. AU - Kroll, J. PY - 2010 DA - 2010// TI - The Rac1 regulator ELMO1 controls vascular morphogenesis in zebrafish JO - Circ Res VL - 107 UR - https://doi.org/10.1161/CIRCRESAHA.109.213983 DO - 10.1161/CIRCRESAHA.109.213983 ID - Epting2010 ER - TY - JOUR AU - Zhang, S. AU - Huang, W. C. AU - Li, P. AU - Guo, H. AU - Poh, S. B. AU - Brady, S. W. PY - 2011 DA - 2011// TI - Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2309 DO - 10.1038/nm.2309 ID - Zhang2011 ER - TY - JOUR AU - Payne, S. L. AU - Hendrix, M. J. AU - Kirschmann, D. A. PY - 2006 DA - 2006// TI - Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex JO - J Cell Biochem VL - 98 UR - https://doi.org/10.1002/jcb.20792 DO - 10.1002/jcb.20792 ID - Payne2006 ER - TY - JOUR AU - Inuzuka, T. AU - Tsuda, M. AU - Kawaguchi, H. AU - Ohba, Y. PY - 2009 DA - 2009// TI - Transcription factor 8 activates R-Ras to regulate angiogenesis JO - Biochem Biophys Res Commun VL - 379 UR - https://doi.org/10.1016/j.bbrc.2008.12.101 DO - 10.1016/j.bbrc.2008.12.101 ID - Inuzuka2009 ER -