Fig. 3
From: Orai/CRACM1 and KCa3.1 ion channels interact in the human lung mast cell plasma membrane
FcεRI- and 1-EBIO-dependent HLMC KCa3.1 currents are inhibited by expression of an Orai1-E106Q dominant-negative mutant. Transduction of HLMCs with an Orai1-E106Q dominant-negative mutant ablated (a) 1-EBIO- dependent and (b) FcεRI-dependent KCa3.1 currents. For clarity, data are presented as the subtracted net activation-dependent currents (activation minus baseline) for each condition, expressed as mean ± SEM