Fig. 3From: Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomesThe Tks4R43W mutant protein colocalizes with the microtubule network of the cytoskeleton. COS7 cells were transiently transfected with wild type V5-Tks4 (3g, h, i), V5-Tks4R43W (3j, k, l) or V5-empty (3d, e, f) constructs. Non-transfected cells are also shown (3a, b,c). After 18 h, cells were fixed and stained for Tks4 (with anti-V5 antibody, red, 3b, e, j, k) and α-tubulin (green, 3a, d, g, j). Merged pictures are also shown (3c, f, i, l). Cell nuclei were visualized by DAPI staining. The scale bar represents 10 μmBack to article page