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Figure 3 | Cell Communication and Signaling

Figure 3

From: Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

Figure 3

Differences in signalling component transcript changes between EGF and hypoxia induced EMT. Changes in transcript abundance (legend top right) for selected intracellular signalling components, within a schematic representation of the signalling network interactions between encoded proteins. Note the use of alternative colour-bars to indicate statistically significant (**; q-value < 0.05; red-green) and non-significant (brown/orange-teal) changes in abundance. Kinase inhibitors within the families selected for screening (described in text; shown in purple) are listed in Table 3.

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