Figure 1From: Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma Schematics of EGFR signaling via PI3K and AKT. Graphics depicting cell membrane, nucleus and transcription taken from motifolio.com. This is an oversimplified view of the network. In reality, for example, crosstalks between different canonical pathways, such as between RAS and PI3K, and multiple feedback loops are also observed as discussed in the next sections.Back to article page